project
The DETOX Project
1 January 2016 - 1 January 2021
PI/s in Exeter: Kate Tresidder
Research partners: Universities of York (PI: Prof. Gavin H. Thomas); Sheffield, Nottingham and Cambridge
Sponsor(s): BBSRC
Project webpage(s)
About the research
Project DETOX was launched in
2016 through the award of a 5-year Translation Grant through the Industrial
Biotechnology Catalyst (Innovate UK, BBSRC, EPSRC). It is led from the Department of Biology at the
University of York by Dr. Gavin H. Thomas with collaborators at the
Universities of Nottingham, Sheffield, Exeter and Cambridge. Working with industrial partners Lucite, Green Biologics,
Ingenza and CPI, the team aim to understand the physiological changes that
microbes use to enable survival when exposed to bio-manufacturing chemicals
that are toxic to them. DETOX solutions will then provide engineered chassis
strains for its key partners for use in bioproduction to yield higher final
titres of product – a problem that currently limits the financial viability of
some processes.
Co-investigator Professor Susan Molyneux-Hodgson and Research Associate Sally Atkinson from the University of Exeter are in charge of the Responsible Research and Innovation component of the project.
More information on the DETOX Project