project

The DETOX-Responsible Innovation Project

1 January 2016 - 1 January 2021

PI/s in Exeter: Professor Susan Molyneux-Hodgson

Research partners: Academic research partners: Universities of York (PI: Prof. Gavin H. Thomas); Sheffield, Nottingham and Cambridge Industrial partnerships: Lucite International, Green Biologics, Ingenza, and CPI.

Sponsor(s): BBSRC

About the research

Project DETOX was launched in 2016 through the award of a 5-year Translation Grant through the Industrial Biotechnology Catalyst (Innovate UK, BBSRC, EPSRC). It is led from the Department of Biology at the University of York by Dr. Gavin H. Thomas with collaborators at the Universities of Nottingham, Sheffield, Exeter and Cambridge. Working with industrial partners Lucite, Green Biologics, Ingenza and CPI, the team aim to understand the physiological changes that microbes use to enable survival when exposed to bio-manufacturing chemicals that are toxic to them. DETOX solutions will then provide engineered chassis strains for its key partners for use in bioproduction to yield higher final titres of product – a problem that currently limits the financial viability of some processes.

Co-investigator Professor Susan Molyneux-Hodgson and Research Associate Sally Atkinson from the University of Exeter are in charge of the Responsible Research and Innovation component of the project.

More information on the DETOX Project